DNA Designer Defects in Photonic Crystals: Optically Monitored Biochemistry
Biomolecules have been incorporated as designed planar defect layers in colloidal photonic crystals using self- assembly techniques (see figure). Through shifts of the photonic intragap defect mode, for example, DNA conformational changes and the enantioselective intercalation of a chiral anticancer drug can be optically monitored. This newfound capability for optically monitoring biochemistry bodes well for the development of a new generation of simple on-the-spot color readout biosensors.
Fleischhaker, F., Arsenault, A. C., Peiris, F. C., Kitaev, V., Manners, I., Zentel, R. and Ozin, G. A. (2006), DNA Designer Defects in Photonic Crystals: Optically Monitored Biochemistry. Adv. Mater., 18: 2387–2391. doi:10.1002/adma.200600579.