Acid and Base Stress and Transcriptomic Responses in Bacillus subtilis
Acid and base environmental stress responses were investigated in Bacillus subtilis. B. subtilis AG174 cultures in buffered potassium-modified Luria broth were switched from pH 8.5 to pH 6.0 and recovered growth rapidly, whereas cultures switched from pH 6.0 to pH 8.5 showed a long lag time. Log-phase cultures at pH 6.0 survived 60 to 100% at pH 4.5, whereas cells grown at pH 7.0 survived
Wilks, J. C.,* R. D. Kitko, S. H. Cleeton,* G. Lee,* C. S. Ugwu,* B. D. Jones, S. S. BonDurant, and J. L. Slonczewski. 2009. Acid and base stress and transcriptomic responses in Bacillus subtilis. Appl. Env. Microbiol.75: 981-990.
Applied and Environmental Microbiology